CMAR

Publications

Peer Reviewed Publications

Our peer-reviewed publications are organised in line with our research themes. Please expand theme sections below for more information. This list is not exhaustive.

  • Crossland, H., Skirrow, S. and Puthucheary, Z. et al. (2018) The impact of immobilisation and inflammation on the regulation of muscle mass and insulin resistance: different routes to similar end‐points. The Journal of Physiology, 597 (5): 1259-1270.
  • Cucchi, D., Camacho-Muñoz, D. and Certo, M. et al. (2019) Omega-3 polyunsaturated fatty acids impinge on CD4+ T cell motility and adipose tissue distribution via direct and lipid mediator-dependent effects. Cardiovascular Research.
  • Filer, A., Ward, L. and Kemble, S. et al. (2017) Identification of a transitional fibroblast function in very early rheumatoid arthritis. Annals of the Rheumatic Diseases, 76 (12): 2105-2112.
  • Gnimassou, O., Fernández‐Verdejo, R. and Brook, M. et al. (2018) Environmental hypoxia favors myoblast differentiation and fast phenotype but blunts activation of protein synthesis after resistance exercise in human skeletal muscle. The FASEB Journal, 32 (10): 5272-5284.
  • Lazarus, N., Lord, J. and Harridge, S. (2018) The relationships and interactions between age, exercise and physiological function. The Journal of Physiology, 597 (5): 1299-1309.
  • Macfadyen, M., Daniel, Z. and Kelly, S. et al. (2019) The commercial pig as a model of spontaneously-occurring osteoarthritis. BMC Musculoskeletal Disorders, 20 (1).
  • Mackenzie, S. and Reynolds, R. (2018) Differential effects of vision upon the accuracy and precision of vestibular-evoked balance responses. The Journal of Physiology, 596 (11): 2173-2184.
  • Mckendry, J., Breen, L. and Shad, B. et al. (2018) Muscle morphology and performance in master athletes: A systematic review and meta-analyses. Ageing Research Reviews, 45: 62-82.
  • Phillips, B., Williams, J. and Greenhaff, P. et al. (2017) Physiological adaptations to resistance exercise as a function of age. JCI Insight, 2 (17).
  • Piasecki, M., Ireland, A. and Piasecki, J. et al. (2018) Failure to expand the motor unit size to compensate for declining motor unit numbers distinguishes sarcopenic from non-sarcopenic older men. The Journal of Physiology, 596 (9): 1627-1637.
  • Pollock, R., O’Brien, K. and Daniels, L. et al. (2018) Properties of the vastus lateralis muscle in relation to age and physiological function in master cyclists aged 55-79 years. Aging Cell, 17 (2): e12735.
  • Pandey, P., Yang, J. and Tsitsipatis, D. et al. (2020) circSamd4 represses myogenic transcriptional activity of PUR proteins. Nucleic Acids Research, 48 (7): 3789-3805.
  • Pucino, V., Certo, M. and Bulusu, V. et al. (2019) Lactate Buildup at the Site of Chronic Inflammation Promotes Disease by Inducing CD4+ T Cell Metabolic Rewiring. Cell Metabolism, 30 (6): 1055-1074.e8.
  • Seabright, A., Fine, N. and Barlow, J. et al. (2020) AMPK activation induces mitophagy and promotes mitochondrial fission while activating TBK1 in a PINK1‐Parkin independent manner. The FASEB Journal, 34 (5): 6284-6301.
  • Smith, C., Allsop, J. and Mistry, M. et al. (2017) Co-ordination of the upper and lower limbs for vestibular control of balance. The Journal of Physiology, 595 (21): 6771-6782. 
  • Timmons, J., Volmar, C. and Crossland, H. et al. (2019) Longevity‐related molecular pathways are subject to midlife “switch” in humans. Aging Cell, 18 (4).
  • Wilkinson, D., Hossain, T. and Limb, M. et al. (2018) Impact of the calcium form of β-hydroxy-β-methylbutyrate upon human skeletal muscle protein metabolism. Clinical Nutrition, 37 (6): 2068-2075.
  • Amara, K., Clay, E. and Yeo, L. et al. (2017) B cells expressing the IgA receptor FcRL4 participate in the autoimmune response in patients with rheumatoid arthritis. Journal of Autoimmunity, 81: 34-43.
  • Bustamante, M., Oliveira, P. and Garcia-Carbonell, R. et al. (2018) Hexokinase 2 as a novel selective metabolic target for rheumatoid arthritis. Annals of the Rheumatic Diseases, 77 (11): 1636-1643.
  • Chowdhury, A., Adiamah, A. and Kushairi, A. et al. (2020) Perioperative Probiotics or Synbiotics in Adults Undergoing Elective Abdominal Surgery. Annals of Surgery, 271 (6): 1036-1047.
  • Croft, A., Campos, J. and Jansen, K. et al. (2019) Distinct fibroblast subsets drive inflammation and damage in arthritis. Nature, 570 (7760): 246-251.
  • Dakin, S., Coles, M. and Sherlock, J. et al. (2018) Pathogenic stromal cells as therapeutic targets in joint inflammation. Nature Reviews Rheumatology, 14 (12): 714-726.
  • Nanus, D., Wijesinghe, S. and Pearson, M. et al. (2020) Regulation of the Inflammatory Synovial Fibroblast Phenotype by Metastasis‐Associated Lung Adenocarcinoma Transcript 1 Long Noncoding RNA in Obese Patients With Osteoarthritis. Arthritis & Rheumatology, 72 (4): 609-619.
  • Zhang, F., Wei, K. and Slowikowski, K. et al. (2019) Defining inflammatory cell states in rheumatoid arthritis joint synovial tissues by integrating single-cell transcriptomics and mass cytometry. Nature Immunology, 20 (7): 928-942.
  • Grönwall, C., Amara, K. and Hardt, U. et al. (2017) Autoreactivity to malondialdehyde-modifications in rheumatoid arthritis is linked to disease activity and synovial pathogenesis. Journal of Autoimmunity, 84: 29-45.
  • Hardy, R., Fenton, C. and Croft, A. et al. (2018) 11 Beta-hydroxysteroid dehydrogenase type 1 regulates synovitis, joint destruction, and systemic bone loss in chronic polyarthritis. Journal of Autoimmunity, 92: 104-113. 
  • Humby, F., Lewis, M. and Ramamoorthi, N. et al. (2019) Synovial cellular and molecular signatures stratify clinical response to csDMARD therapy and predict radiographic progression in early rheumatoid arthritis patients. Annals of the Rheumatic Diseases, 78 (6): 761-772.
  • Lobo, D. (2019) Improving outcomes with a little EFFORT. The Lancet, 393 (10188): 2278-2280.
  • McGrath, C. and Young, S. (2018) Can metabolomic profiling predict response to therapy?. Nature Reviews Rheumatology, 15 (3): 129-130.
  • Mizoguchi, F., Slowikowski, K. and Wei, K. et al. (2018) Functionally distinct disease-associated fibroblast subsets in rheumatoid arthritis. Nature Communications, 9 (1).
  • Mohan, D., Forman, J. and Allinder, M. et al. (2018) Fibrinogen does not relate to cardiovascular or muscle manifestations in COPD: cross-sectional data from the ERICA study. Thorax, 73 (12): 1182-1185.
  • Puthucheary, Z., Astin, R. and Mcphail, M. et al. (2018) Metabolic phenotype of skeletal muscle in early critical illness. Thorax, 73 (10): 926-935.
  • Nayar, S., Campos, J. and Smith, C. et al. (2019) Immunofibroblasts are pivotal drivers of tertiary lymphoid structure formation and local pathology. Proceedings of the National Academy of Sciences, 116 (27): 13490-13497.
  • Aungier, S., Cartwright, A. and Schwenzer, A. et al. (2018) Targeting early changes in the synovial microenvironment: a new class of immunomodulatory therapy?. Annals of the Rheumatic Diseases, 78 (2): 186-191.
  • Wilson, D., Jackson, T. and Sapey, E. et al. (2017) Frailty and sarcopenia: The potential role of an aged immune system. Ageing Research Reviews, 36: 1-10.
  • Cooke, M., Jones, S. and ter Horst, B. et al. (2018) Structuring of Hydrogels across Multiple Length Scales for Biomedical Applications. Advanced Materials, 30 (14): 1705013.
  • D’Hulst, G., Soro-Arnaiz, I. and Masschelein, E. et al. (2020) PHD1 controls muscle mTORC1 in a hydroxylation-independent manner by stabilizing leucyl tRNA synthetase. Nature Communications, 11 (1).
  • Din, U., Brook, M. and Selby, A. et al. (2019) A double-blind placebo controlled trial into the impacts of HMB supplementation and exercise on free-living muscle protein synthesis, muscle mass and function, in older adults. Clinical Nutrition, 38 (5): 2071-2078.
  • Elhassan, Y., Kluckova, K. and Fletcher, R. et al. (2019) Nicotinamide Riboside Augments the Aged Human Skeletal Muscle NAD+ Metabolome and Induces Transcriptomic and Anti-inflammatory Signatures. Cell Reports, 28 (7): 1717-1728.e6.
  • Gonzalez, J., Richardson, J. and Chowdhury, E. et al. (2017) Molecular adaptations of adipose tissue to 6 weeks of morning fasting vs. daily breakfast consumption in lean and obese adults. The Journal of Physiology, 596 (4): 609-622.
  • Hossain, T., Phillips, B. and Doleman, B. et al. (2019) A double-blind randomized controlled trial of the effects of eicosapentaenoic acid supplementation on muscle inflammation and physical function in patients undergoing colorectal cancer resection. Clinical Nutrition.
  • Perrin, L., Loizides-Mangold, U. and Chanon, S. et al. (2018) Transcriptomic analyses reveal rhythmic and CLOCK-driven pathways in human skeletal muscle. eLife, 7.
  • Duggal, N., Niemiro, G. and Harridge, S. et al. (2019) Can physical activity ameliorate immunosenescence and thereby reduce age-related multi-morbidity?. Nature Reviews Immunology, 19 (9): 563-572.
  • Smeuninx, B., Nishimura, Y. and McKendry, J. et al. (2019) The effect of acute oral phosphatidic acid ingestion on myofibrillar protein synthesis and intracellular signaling in older males. Clinical Nutrition, 38 (3): 1423-1432.
  • Wilkinson, D., Bukhari, S. and Phillips, B. et al. (2018) Effects of leucine-enriched essential amino acid and whey protein bolus dosing upon skeletal muscle protein synthesis at rest and after exercise in older women. Clinical Nutrition, 37 (6): 2011-2021.
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