Beth’s work focuses on the pathophysiology of musculoskeletal morbidities (sarcopenia, cachexia, arthritis, disuse, metabolic syndrome etc.) and interventions to mitigate their progression and consequences. Combining molecular biology, stable isotope methodologies and detailed in vivo human physiology, Beth has been a key part of a team that has uncovered fundamental parameters governing alterations in musculoskeletal metabolism with ageing and disease. The unique aspect of Beth’s research is combining detailed in vivo human physiology with state-of-the-art vascular imaging methodologies to determine links between vascular function (including the musculoskeletal microvasculature) and metabolic dysregulation in ageing and disease and in the context of exercise-, nutrition- and pharmacological-based interventions. Latterly, Beth has also been involved in the application of OMIC technologies to discover predictors of, and the basis for, the musculoskeletal and vascular decline in ageing and age-associated disease. Beth’s future focus is aimed at investigating the mechanisms of, and developing predictors for, the heterogeneous metabolic and physiological improvements in responses to exercise-for-health interventions. Beth also has a strong interest in developing optimal exercise training interventions around clinical constraints (e.g. time to surgery) to improve physical function in various clinical cohorts (i.e. colorectal cancer, rheumatoid arthritis). Beth has significant involvement with and experience in numerous aspects of research relating to postgraduate training, ethics and scientific outreach.